Von Willebrand Disease Test Questions

1. A 24-year-old woman presents with severe menorrhagia. A pregnancy test is negative. The most common coagulopathy associated with menorrhagia is?

a. Hemophilia A (FALSE) Hemophilia A is the most common type of hemophilia not the most common hereditary bleeding disorder)

b. Hemophilia B (FALSE) Hemophilia B is the 2^nd most common type of hemophilia also known as the Christmas Disease

c. von Willebrand's disease (TRUE) vWD is the most common hereditary bleeding (Coagulation) disorder. It is also the leading coagulapthy associated with adolescent menorrhagia.

d. Factor V Leiden (FALSE) Factor V is the most common hereditary hypercoagulability disorder.

2. As a Family Nurse Practitioner, you have a 25-year old female patient that presents to you with Type II von Willebrand’s Disease and you are deciding what treatment is needed for this patient. Which of the following is the most recommended birth control method for patients who have vWD?

a. Morphone (FALSE) Narcotics were not even discussed in this paper.

b. Aspirin (FALSE) Aspirin aggravates bleeding and interferes with platelet function.

c. Combined Contraceptives (TRUE) Combined oral contraceptives are the most recommended birth control for patients who have vWD.

d. Heparin (FALSE) Since bleeding and hemorrhages are a characteristic of this condition, Heparin should not be given since it aggravates bleeding

3. A patient presents to your clinic requesting more information on vWD. She is trying to get pregnant and is worried that she will pass it on to her child. Your best response should be:

a. You have a 50% chance of passing it on only if you have a son. (FALSE) vWD affects males/females equally.

b. You have a 75% chance of passing the gene on to his/her child. (FALSE) A man or woman with vWD has a 50% chance of passing the gene on to his/her child.

c. vWD primarily affects African Americans which puts you at low risk for passing it on to your child. (FALSE ) There is no racial or ethnic associations associated with the vWD

d. vWD is a genetic disease that affects males and females equally, thus giving you a 50% chance of passing on the gene to your child. (TRUE)

4. Which of the following risks are greater in pregnant women who have vWD?

a. Post Partum Hemorrhage and excessive bleeding in the mother after delivery (TRUE)

b. Gestational diabetes (FALSE) women with vWD are less likely to develop gestational diabetes.

c. Pre-eclampsia (FALSE) Women with vWD were no more likely to develop this pregnancy complication than those without it.

d. Intrauterine (fetal) growth restriction. (FALSE) Women with vWD were no more likely to develop this pregnancy complications than those without it.

5. A 28-year old patient has recently been treated with oral contraceptives for vWD and wants to know the benefits of this type of method. Which of the following is the best explanation that can be given for this patient?

a. Combined Oral Contraceptives are used to suppress ovulation and thought to reflect an estrogen-induced increase in vWF and Factor VIII levels. (TRUE)

b. Combined Oral Contraceptives are used to suppress ovulation and thought to decrease risk of atherosclerotic events. (FALSE) While, COC are used to suppress ovulation and increase vWF and factor VIII, they are not beneficial for decreasing atherosclerotic events. This is a disadvantage/con of combined oral contraceptives).

c. Combined Oral Contraceptives are used to suppress ovulation, increase vWF and factor VIII levels while decreasing a patient’s risk for a stroke. (FALSE) While, COC are used to suppress ovulation and increase vWF and factor VIII, they are not beneficial for decreasing a stroke. This is a disadvantage/con of combined oral contraceptives).

d. Combined Oral Contraceptives are used to suppress ovulation, increase vWF and factor VIII levels while decreasing a patient’s risk for a Myocardial Infarction (MI). (FALSE) While, COC are used to suppress ovulation and increase vWF and factor VIII, they are not beneficial for decreasing a MI. This is a disadvantage/con of combined oral contraceptives)